90% of cases present with respiratory symptoms.
Associated features to be aware of include:
- blood nasal discharge
- saddle-shaped nose
75% get crescentic glomerulonephritis.
cANCA is positive in 90%, pANCA is positive in 25%
CXR may show large shadows. Pulmonary haemorrhage is also possible.
Treatment is with steroids, cyclophosphamide and possibly co-trimaoxazole to try and reduce risk of PCP.
I guess this is a good opportunity to reconfront a personal demon in the form of a renal battle...