MRCP revision battle 22.5: Fanconi Syndrome

Fanconi syndrome is disturbance of proximal renal tubule function, resulting in defective reabsorption of:

• amino acids
• phosphate
• potassium
• glucose
• bicarbonate

It can cause vitamin D resistant rickets.

Causes of Fanconi syndrome include:

• idiopathic
• inherited
• cystinosis
• Wilson's disease
• acquired
• heavy metal poisoning
• light chains
• amyloid
• myloma

Treatment is:

• treat cause
• replace losses (potassium, bicarb, phosphate, vit D supplements)

Lets now move back mainstream with a revision battle with aortic regurgitation...