Saturday, 11 September 2010

MRCP revision battle 8.6: Romano Ward and Jervell-Lange-Nielson Syndomes

Both Romano-Ward and Jervell-Lange-Nielson Syndrome are congenitial causes of a long QT.

Both are believed to be caused by mutations in the potassium subunit.

The differences are:
  1. Romano-Ward is autosomal dominant while Jervell-Lange-Nielson is autosomal recessive
  2. Jervell-Lange-Nielson is associated with bilateral deafness; Romano Ward is not.

Thats all for today; if you want to test your recall of topics covered yesterday click here