Sunday, 17 October 2010

MRCP revision battle 32.5: Macular degeneration

Macular degeneration is the commonest cause of blindness in the UK.

There are 2 types:
  • dry 
    • drusen - yellow spots in Bruchs membrane
  • wet
    • choroidal neovascularisation
    • worse prognosis

Below is an image of dry macular degeneration showing drusen.  To link to an image of wet macular degeneration click here

Risk factors for macular degeneration are:
  • age >60
  • female
  • smoking
  • caucasian
  • family history

Treatment - there is no cure:
  • high dose beta caratene - but may increase risk of lung cancer in smokers
  • vitamin C and E - but vit E may increase risk of heart failure
  • zinc
  • for wet:
    • photocoagulation
    • anti VEGF
    • Ranibizumab
    • photodynamic therapy

Keeping on eyes, next up is glaucoma...