The classic triad of Behcet's disease is:
- oral ulcers
- genital ulcers
- anterior uveitus
Other possible features include:
- erythema nodosum
- pathergy reaction (=needle prick leads to pustule formation)
- aseptic meningitis
Males are more commonly affected than females.
It is commonest in Turkey and Japan.
30% of patients have a positive family history.
HLA B5 is associated with anterior uveitis and HLA B12 is associated with recurrent ulceration.
Severe disease requires steroids/ciclosporin/azathioprine.
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