Primary = essential thrombocythaemia
- caused by a clonal proliferation of megakaryocytes
- platelets typically >1000 (x10 to the power 9)
- abnormal function, risking either thrombosis or bleeding
- treatment = aspirin. Hydroxycarbamide is given to lower platelets if pt is >60yrs or they have had a previous thrombosis
Secondary thrombocytosis
- reactive to
- bleeding
- infection
- trauma
- thrombosis
- infarction
- iron deficiency
Now for some haemophilia....