MRCP revision battle 50.1: Gangrene and necrotising fasciitis
MRCP revision battle 50.2: Acne Rosacea
MRCP revision battle 50.3: Seborrhoeic dermatitis
MRCP revision battle 50.4: Alopecia
MRCP revision battle 50.5: Discoid lupus erythematosus
MRCP revision battle 50.6: Bullous Pemphigoid and Pemphigus Vulgaris
MRCP revision battle 50.7: Erythrasma
MRCP revision battle 50.1: Gangrene and necrotising fasciitis
A couple of grim topics: gangrene and necrotising fasciitis.
Gangrene
Gangrene is death of tissue due to ischaemia. It can be subdivided into:
- dry gangrene = ischaemia only
- wet gangrene = ischaemia plus infection
Management is surgical with debridement and IV antibiotics
Necrotising fasciitis
Necrotising fasciitis is a rapidly spreading infection of the deep fascia.
Type 1 is caused by mixed anaerobes and aerobes, classically occuring in diabetes and post surgery
Type 2 is usually caused by streptococcus pyrogenes, which is a group A beta haemolytic strep.
Fournier's gangrene is a subtype of necrotising fasciitis which affects male genitalia/the perineal area.
Meleney's gangrene is a subtype of necrotising fasciitis which occurs after an operation
Treatment of necrotising fasciitis is with debridement.
Mortality is around 70%.
Onwards to acne rosacea...