Sunday, 21 November 2010

MRCP revision battle 56.3: P450 inducers and inhibitors

P450 inducers include:
  • rifampicin
  • antiepileptics except sodium valproate
  • griseofulvin
  • smoking
  • st johns wort
  • barbituates
  • chronic alcohol

P450 inhibitors include:
  • anti-infection meds
    • ciprofloxacin
    • erythromycin
    • ketoconazole
    • isoniazid
  • Anti reflux
    • cimetidine
    • omeprazole
  • Pysch meds
    • SSRIs
    • antipyschotics
    • TCA
  •  sodium valproate
  • acute alcohol
  • class IV antiarrhymics
    • diltiazen
    • verapamil