Maternal rubella
- fetus is nearly always affected if rubella occurs during first 7 weeks of gestation
- fetus is nearly always OK if rubella occurs after 17 weeks of gestation
- Effects of rubella on fetus:
- sensorineural deafness
- congenital cateracts
- congenital heart disease
- glaucoma
Maternal toxoplasmosis
- fetus will only be affected if it is the first time the mother is exposed, unless she is immunosupressed
- classical triad is:
- cerebral calcification
- hydrocelphalus
- chorioretinitis
Maternal chickenpox
- if this occurs during the 1st trimester risk of limb deformity
- if mum has been in contact with chickenpox and is not sure if she is immune test for antibodies and if no natural immunity give immunoglobulin
Maternal CMV
- at least 75% of fetus' exposed to CMV are undamaged
- however, there is a risk of:
- intracranial calcification
- microcephaly
- cardiac/GI abnormalities
Maternal Parvovirus B19
- generally either fetal death or complete recovery
Now for a spot of rheumatoid factor
