Friday, 12 November 2010

MRCP revision battle 47.2: Diffuse proliferative glomerulonephritis



Diffuse proliferative glomerulonephritis classically presents after a streptococcal infection or impetigo.  It tends to affect children and young adults.


Diffuse proliferative glomerulonephritis tends to cause nephritic syndrome or acute renal failure.


Immunofluorescence shows C3 and IgG.
Serology shows decreased C3 and raised ASOT


Treatment is supportive and >95% recover.


Now lets consider nephritis...